Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics
نویسندگان
چکیده
منابع مشابه
Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics.
Proteasomes are ubiquitously expressed multicatalytic complexes that serve as key regulators of protein homeostasis. There are several lines of evidence indicating that proteasomes exist in heterogeneous subpopulations in cardiac muscle, differentiated, in part, by post-translational modifications (PTMs). PTMs regulate numerous facets of proteasome function, including catalytic activities, comp...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2012
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00189.2012